Christelle Huguet, Ph.D.

Chair, Scientific Advisory Board

Dr. Huguet brings 20 years of drug discovery and development experience, most recently as Chief Scientific Officer of X-Chem Pharmaceuticals.  Prior to X-Chem, Dr. Huguet was Head of Internal Research at Alexion focusing on rare and devastating diseases. Dr. Huguet previously held a number of leadership positions at Pfizer, including Chief Scientific Officer of the Inflammation & Remodeling Research Unit, Chief Scientific Officer of Worldwide Pharmacokinetics Dynamics & Metabolism, Head of the Genito-Urinary Therapeutic Area, Head of Allergy & Respiratory Research.  Dr. Huguet directed strategy and research in rare diseases, sexual health, endometriosis, overactive bladder, incontinence, interstitial cystitis, chronic pulmonary diseases and chronic kidney diseases.  Dr. Huguet has delivered more than 10 NMEs spanning small molecules, RNAs, biologics, oral, inhaled and/or injectables, and led several programs into PhI and Phase IIa/b clinical trials.

Dr. Huguet studied in France, Germany and Switzerland, receiving a French University Diploma in Technology (DUT) in applied biology and biochemistry, and a European Engineering degree in biotechnology sciences. She received a Ph.D. in molecular and cellular biology from the Institute Pasteur in France.

Other Team Members

Ed Koval

Chief Business Officer

Christelle Huguet, Ph.D.

Chair, Scientific Advisory Board

Richard Wagner, Ph.D.

Founder and Director

John Cuozzo Ph.D

SVP and Head of Drug Discovery

Brant Binder


Brian Goldman, Ph.D.

SVP and Chief Computation Scientist

Rafael Gomez-Bombarelli, Ph.D.

Chief Learning Officer